In 1800, Nettie was born in Arkansas. She was turned at the age of 26 by Haden, who became her lover. Along with an unnamed male vampire, they built a civilized coven, but it was soon destroyed by another coven. Both Haden and his coven mate were killed which left Nettie devastated and a thirst for vengeance. As a result to the lost battle, Nettie was driven out of Arkansas. When she met Lucy and Maria, both survivors of their fallen covens, they formed an alliance out of convenience. Maria and Lucy wanted revenge for their mates lost in battle, while Nettie was eager to replace her lost hunting grounds in Arkansas and the safety of numbers.
Together, the three of them began to build an army of newborn vampires, though she was not very involved due to her lack of self-control. Maria wanted to use newborns with training from a human army and politics in order to make the army work more effectively. After Maria turned Jasper Whitlock, a major of the Texas cavalry, they not only reclaimed their lost territories, but also won many other territories and the three of them were delighted. Some time later though, Lucy and Nettie began feeling malicious towards Maria. Nettie suggested to Lucy that they kill Maria and Jasper to take over the coven. However, their malicious feelings alerted Jasper of their impending betrayal because of his ability to feel emotions of those around him. Maria and Jasper surprised them with a preemptive attack and Nettie, along with Lucy, was executed.
From description, Nettie was likely a very devious and malicious character who loved power more than anything, similar to Caius. Because of her lack of self-restraint, she rarely participated in Maria's creations to her army.